ABSTRACT
Objective To evaluate the value of magnetic resonance spectroscopy (MRS) in the diagnosis of intracranial space-occupying lesions. Methods A total of 126 patients with intracranial space-occupying lesions in the First Affiliated Hospital of Xinjiang Medical University from 2019 to 2022 were enrolled and subjected to brain magnetic resonance imaging (MRI) and MRS examinations. The performance of MRI alone and in combination with MRS was evaluated and compared for diagnosis of intracranial space-occupying lesions. Results Tuberculoma (19.05%) and high-grade glioma (15.87%) were the intracranial space-occupying lesions most commonly diagnosed by MRI in combination with MRS. Radiologists confirmed the diagnosis of intracranial space-occupying lesions in 23.81% patients depending on MRI alone, and in 75.40% patients depending on MRI combined with MRS, with a 2.17-fold improvement (χ2 = 67.07, P<0.01). The combination of MRI and MRS improved the accuracy of imaging diagnosis of intracranial space-occupying lesions in 70 (55.67%) patients compared with MRI alone. In addition, MRI in combination with MRS significantly improved the accuracy of differential diagnosis of high-grade glioma, low-grade glioma, cerebral infarct, tuberculoma, recurrent tumor, and radiation necrosis compared with MRI alone (P<0.01). Conclusion The efficacy of imaging diagnosis of intracranial space-occupying lesions can be improved by MRI in combination with MRS relative to MRI alone. The combined use of MRI and MRS may serve as a non-invasive tool for diagnosis of intracranial space-occupying lesions. In addition, the combination facilitates the differentiation between low- and high-grade gliomas, between high-grade glioma and tuberculoma, and between recurrent tumor and radiation necrosis.
ABSTRACT
Objective To explore the relationship between conventional MRI characteristics and clinical stage of hepatic alveolar echinococcosis(HAE).Methods 54 patients diagnosed with HAE in our hospital were collected.The characteristics of HAE in conventional MRI were analyzed,and the correlationship among the Kodama classification,the maximum diameter of the lesion and the clinical stage of PNM were compared.Results According to the Kodama classification,the lesions were divided into 5 types:Kodama type 1 (2.63%,2/76), Kodama type 2 (18.42%,14/76),Kodama type 3 (51.32%,39/76),Kodama type 4 (26.32%,20/76)and Kodama type 5 (1.32%,1/76).In this study,22.37% (17/76)lesions were at P1 stage,7.89% (6/76)lesions were at P2 stage,60.53% (46/76)lesions were at P3 stage, 9.21% (7/76)lesions were at P4 stage.44.74% (34/76)lesions were at N1 stage.18.42% (14/76)lesions were at M1 stage.P stage and N stage were positively correlated with the maximum diameter of the lesions (P<0.000,r=0.516;P<0.000,r=0.754).Conclusion There is no correlation between the Kodama typing and the maximum diameter of the lesions.P and N staging is positively correlated with the maximum diameter of the lesions.There is no correlation between M staging and the maximum diameter of the lesions.